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Mark Slabodnick
Associate Professor of Biology
Meet Professor Slabodnick
Years at Knox: 2020 to present
Email Professor Slabodnick: mmslabodnick@knox.edu
"The diversity of organisms that fills the world has always fascinated me. Both for large multicellular organisms like an oak tree, an elephant, or a human as well as single-celled organisms like paramecium or dinoflagellate, there are seemingly endless forms and shapes that they can take. In my lab I use the understudied unicellular organism Stentor coeruleus as a model to study how these amazing cells are able to generate, and regenerate, their complex anatomy. Even though they are just one cell, S. coeruleus can be up to 1 millimeter in length and can be seen without the aid of a microscope. Even more amazing is that when the cell is injured, or even physically cut in half, they can fully regenerate and replace any of the missing structures with incredible precision. We use a mixture of cell and molecular biology as well as genetics to investigate the genes required to build, and regenerate these amazing cells."
Education
Ph.D., Biology, 2014, University of California, San Francisco
B.S., Biology, 2007, Ohio State University
Teaching Interests
Cell Biology, Microscopy, Molecular Biology, and Genetics
Selected Professional Accomplishments
Honors/Grants
NIH F32 Fellowship-NIGMS F34GM119348, 2016-2018
ARCS Fellowship, UC, San Francisco, 2011-2013
College of the Arts and Sciences Honors Scholarship, Ohio State University, 2006
TELR Research on Research Fellowshop, Ohio State University, 2005
Publications
Slabodnick, M. M., Ruby, J.G., Reiff, S.B., Swart, E. C., Gosai, S., Prabakaran, S., Witkowska, E., Larue, G.E., Fisher, S., Freeman Jr., R.M., Gunawardena, J., Chu, W., Stover, N.A., Gregory, B.D., Nowacki, M., Derisi, J., Roy, S.W., Marshall, W.F., Sood, P. The Macronuclear Genome of Stentor coeruleus Reveals Tiny Introns in a Giant Cell. Current Biology 27,569-575 (2017).
Slabodnick, M. M. & Marshall, W. F. Stentor coeruleus. Current Biology 24, R783-R784 (2014).
Slabodnick, M. M., Ruby, J.G., Dunn, J.G., Feldman, J.L., Derisi, J.L., Marshall, W.F. The Kinase Regulator Mob1 Acts as a Patterning Protein for Stentor Morphogenesis. PLoS Biology 12, e1001861 (2014).
Slabodnick, M., Prevo, B., Gross, P., Sheung, J. & Marshall, W. Visualizing Cytoplasmic Flow During Single-cell Wound Healing in Stentor coeruleus. Journal of Visualized Experiments e50848-e50848 (2013). doi:10.3791/50848
Majumder, S., Slabodnick, M., Pike, A., Marquardt, J. & Fisk, H. A. VDAC3 regulates centriole assembly by targeting Mps 1 to centrosomes. Cell Cycle 11,3666-3678 (2012).
Presentations
Triangle Cutoskeleton Meeting, 2019
International Congress of Protistology, 2013
FASEB Ciliate Molecular Biology Conference, 2013
The American Society for Cell Biology, 2012
Gordon Research Conference, Plant and Microbial Cytoskeleton, 2012
The American Society for Cell Biology, 2011