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General Interests
"My research program is devoted to investigating factors that control the size and character of the immune response. This basic information about how cells of the immune system respond to various stimuli has a wide variety of applications, ranging from disease prevention to disease amelioration or cure."
Years at Knox: 1992 to present
Education
Ph.D., Biochemistry and Molecular Biology, 1992, George Washington University.
B.A., Biology and English, 1984, College of William and Mary.
Teaching Interests
Biochemistry, cell biology, cell metabolism, chemistry, immunology, pharmacology
Recent Recognition
Awards
Academic Research Enhancement Award. National Institute of Allergy and Infectious Diseases, National Institutes of Health, 1997-2000.
Fellowships
Missy Tracy Fellow, Institute for Advanced Studies in Immunology and Aging, Washington D.C., 1990-1992.
Recent Accomplishments
Publications
"Inhibition of U937 cytokine secretion by HIV-1 gp120 C4-derived peptide constructs." Co-authored with F.A. Robey. Journal of Bioactive and Compatible Polymers 19 (2004):173-195.
"Temperature alters lipopolysaccharide-induced cytokine secretion by RAW 264.7 cells." Co-authored with Knox students B.J. Thompson and J.S. Coon. Scandinavian Journal of Immunology 58 (2003): 51-58.
"Effect of peptide-carrier coupling on peptide-specific immune responses." Co-authored with A.L. Goldstein and P.H. Naylor. Immunobiology 203 (2001): 601-615.
Presentations
"Hypothermic Inhibition of LPS-Induced iNOS and COX-2 Expression." With A. Giri and B. Thompson, American Association of Immunologists, Boston, Massachusetts.
"Inhibition of Nitric Oxide Secretion in LPS-Stimulated Macrophages by Ethanol." With L. Turnbull, American Association of Immunologists, Boston, Massachusetts.
"Temperature effect on regulation of LPS-induced TNFά secretion." With Knox students B.J. Thompson, C. Martz, and and H. Naci. Experimental Biology /American Association of Immunologists Annual Meeting, San Diego, CA, 2005.
"Temperature influence on activation of NF-κB by LPS in macrophages." With Knox students H. Naci H, Benjamin Thompson, and C. Mill. Experimental Biology /American Association of Immunologists Annual Meeting, San Diego, California, 2005.
"Temperature modulation of endotoxin-stimulated TNF secretion." With Knox student J. Coon. Experimental Biology, New Orleans, Louisiana, 2002.
"Epinephrine modulation of macrophage nitric oxide production." With S. Upadhyay. Experimental Biology, New Orleans, Louisiana, 2002.
"Temperature alters macrophage response to LPS and IFNy." Experimental Biology, New Orleans, Louisiana, 2002.
Campus & Community Involvement
Member, American Association for the Advancement of Science.
Member, American Association of Immunologists.
Member, American Society for Microbiology.
Member, International Society for Interferon and Cytokine Research.
Member, International Society for NeuroImmunoModulation.
Member, Society for Leukocyte Biology.
Contact
309-341-7308
jkirkley@knox.edu
Knox College is one of the top liberal arts colleges in the nation for Fulbright Scholar grants awarded to faculty during 2009-2010. Karen Kampwirth is studying feminism and politics at the University of Buenos Aires, and Jeremy Day O'Connell is conducting musicology and linguistics research at the University of Edinburgh, Scotland.
Knox College is one of the top liberal arts colleges in the nation for Fulbright Scholar grants awarded to faculty during 2009-2010. Karen Kampwirth is studying feminism and politics at the University of Buenos Aires, and Jeremy Day O'Connell is conducting musicology and linguistics research at the University of Edinburgh, Scotland.
The Knox-Sandburg Community Concert Band, Knox Wind Ensemble, and individual music students perform in concert and recital, November 13 through 17 at Knox College.
